(1-(2-HYDROXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER - Names and Identifiers
Name | 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol
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Synonyms | 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl) 1-(2-Hydroxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester (1-(2-HYDROXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER 2-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyrazol-1-yl]ethanol 2-(4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid picol ester 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethan-1-ol, 1-Hydroxy-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethane
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CAS | 1040377-08-9
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(1-(2-HYDROXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER - Physico-chemical Properties
Molecular Formula | C11H19BN2O3
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Molar Mass | 238.09 |
Density | 1.13±0.1 g/cm3(Predicted) |
Boling Point | 379.4±22.0 °C(Predicted) |
pKa | 14.47±0.10(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
(1-(2-HYDROXYETHYL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER - Introduction
2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol, also known as 2-(4-(4,4,5,5-tetramethyl -1,3, 2-dioxaboran-2-yl)-1H-pyrazol-1-yl organic compound) ethanol, is. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-Appearance: White to yellow solid
-Molecular formula: C12H18BNO2
-Molecular weight: 221.09g/mol
-Solubility: Soluble in some organic solvents, such as dimethylformamide (DMF), dimethyl sulfide (DMSO), etc.
-Melting point: about 80-85 ℃
-Use:
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol can be used as a reagent in organic synthesis for the synthesis of compounds containing boronic acid pinacol groups, which has important research and application value.
-It can also be used to synthesize organic compounds such as fluorescent dyes, polymers and drugs.
Preparation Method:
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol has many preparation methods. One of the commonly used methods is to react with pyrazole and 4-bromobutanol, and then react with 4,4, 5,5-tetramethyl -1,3, 2-dioxaborane to obtain the target product.
Safety Information:
- 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol is generally safe for human health, but care should be taken to avoid inhalation of its dust or contact with skin and eyes.
-Avoid prolonged or heavy exposure and use personal protective equipment such as laboratory gloves, safety glasses, etc.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical attention.
Please note that the above information is for reference only. For specific operation and use, please refer to the safety operation manual and technical information provided by the manufacturer, and comply with relevant safety regulations in laboratory and industrial environments.
Last Update:2024-04-09 15:18:01